Findings:
No intra- or extra-axial mass lesion or collection is identified. The midline structures are normal with no midline shift.
No sign of atrophy of the midbrain or the cerebellum.
Marked volume loss is seen involving the mesiotemporal structures on both sides (MTA 4), with relative sparing of the rest of the temporal lobe.
Mild opening of sulci (global cortical atrophy score: 1).
Ventricles are enlarged but are unchanged in size compared to the previous MRI with a maximum biventricular distance of 4.8 cm.
Mild to moderate background small vessel ischaemic disease is seen (Fazekas 2). No evidence of acute infarction.
The visualised paranasal sinuses and the mastoid air cells are clear.
No bony abnormality is seen.
Impression:
Marked atrophy of the hippocampi, typical of Alzheimer disease or limbic-predominant age-related TDP-43 encephalopathy (LATE).