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Multiple sclerosis

Findings:
No intra- or extra-axial mass lesion or collection is identified. The ventricles and sulcal spaces are within normal limits. The midline structures are normal with no midline shift.
A periventricular white matter lesion with partial diffusion restriction is seen adjacent to the left posterior horn. Further, smaller punctiform foci of subcortical white matter lesions are also seen in bilateral frontal white matter. No evidence of any white matter lesions involving the basal ganglia, the brain stem or the cerebellum.
The brain parenchyma is otherwise unremarkable.
The pituitary gland is normal.
The orbits, paranasal sinuses and mastoid air cells are clear.
No bony abnormality is seen. The craniocervical junction is normal.

Conclusion:
Periventricular white matter lesion adjacent to the left posterior horn, suspicious of demyelination. However, the McDonald diagnostic criteria for dissemination in time and space are not fulfilled. Clinical correlation and further evaluation with contrast-enhanced MRI of the whole neuraxis is advised.

Updated on 11. April 2023

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About the author

Dr Sara Mohebbi is a Consultant Radiologist (Facharzt für Radiologie) with sub-specialty training in neuroradiology. She served as Chief Resident at University Hospital Freiburg and is a member of the European Society of Radiology (ESR). Her clinical focus includes demyelinating disease, neuro-oncology, and vascular neuroimaging. Dr Mohebbi is the Clinical Lead at Radiology Prime, where she provides independent second opinion reports on brain and spine MRI.