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Alzheimer’s disease

Findings:
Atrophy of the parietal lobes bilaterally is demonstrated, partially with knife-blade gyral atrophy (Koedam score 2-3 bilaterally).
Moderate enlargement of the temporal horn and mild loss of hippocampal height is seen on the left side (MTA 2) as well as mild widening of the choroid fissure on the right side (MTA 1).
The remainder of the brain is within normal limits for age.
The midline structures are normal with no midline shift. Two tiny lipomas are noted in the subcallosal region.
Multiple FLAIR hyperintense lesions in the supratentorial white matter, confluent in the periventricular regions, are in keeping with moderate small vessel ischemia (Fazekas 2).
No abnormal signal on the diffusion/ADC images is identified.
The pituitary gland is normal.
The orbits, paranasal sinuses and mastoid air cells are clear. Bilateral IOL-implants are seen.
No bony abnormality is seen.
The craniocervical junction is normal.

Conclusion:
Bilateral parietal lobe atrophy, suggestive of Alzheimer’s disease.
Moderate small vessel ischaemic disease.

Updated on 31. March 2023


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About the author

Dr Sara Mohebbi is a Consultant Radiologist (Facharzt für Radiologie) with sub-specialty training in neuroradiology. She served as Chief Resident at University Hospital Freiburg and is a member of the European Society of Radiology (ESR). Her clinical focus includes demyelinating disease, neuro-oncology, and vascular neuroimaging. Dr Mohebbi is the Clinical Lead at Radiology Prime, where she provides independent second opinion reports on brain and spine MRI.