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Alzheimer’s disease

Findings:
No intra- or extra-axial mass lesion or collection is identified. The midline structures are normal with no midline shift.
No sign of atrophy of the midbrain or the cerebellum.
Global cortical atrophy score: 2 – volume loss of gyri and moderate ventricular enlargement.
Koedam score for parietal atrophy: 2 – substantial sulcal widening, substantial gyral atrophy.
Mesial Temporal Atrophy: 2 on the right and 3 on the left side – moderate enlargement of the temporal horn, and moderate loss of hippocampal height.
Mild background small vessel ischaemic disease (Fazekas 1).
No evidence of intracranial haemorrhage or any ischaemic event.
Hyperostosis frontoparietalis is noted. The imaged paranasal sinuses and mastoid air cells are clear. Bilateral IOL-implant is in situ.

Impression:
Bilateral parietal lobe atrophy with asymmetrical hippocampal volume loss (L>R), suggestive of Alzheimer’s disease.

Updated on 6. June 2023

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About the author

Dr Sara Mohebbi is a Consultant Radiologist (Facharzt für Radiologie) with sub-specialty training in neuroradiology. She served as Chief Resident at University Hospital Freiburg and is a member of the European Society of Radiology (ESR). Her clinical focus includes demyelinating disease, neuro-oncology, and vascular neuroimaging. Dr Mohebbi is the Clinical Lead at Radiology Prime, where she provides independent second opinion reports on brain and spine MRI.