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  3. IPILIMUMAB-INDUCED HYPOPHYSITIS

IPILIMUMAB-INDUCED HYPOPHYSITIS

Findings:

The pituitary gland is normal in size. The anterior pituitary shows modest, diffuse, enhancement with some heterogeneity of contrast enhancement across the gland, consistent with hypophysitis. The pituitary stalk is not thickened. Posterior pituitary bright spot is orthotopic in position.

Moderate background small vessel ischaemic disease is noted. The remainder of the imaged brain (please note this study has been targeted to the pituitary, and as such the whole brain has only been imaged on the axial T2 sequence) appears unremarkable.
The orbits, paranasal sinuses and mastoid air cells are clear.
No bony abnormality is seen. The craniocervical junction is normal.

Conclusion:
Heterogeneously enhancing anterior pituitary without obvious enlargement, likely in keeping with residual Ipilimumab-Induced Hypophysitis under treatment. No mass lesion.

Updated on 22. June 2023

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